Description
Orelox is chemically Cefpodoxime proxetil, an antibiotic belonging to the group of 3rd generation cephalosporins. It is active against a wide range of gram-negative and gram-positive organisms. This drug is recommended for the treatment of infections in children caused by organisms sensitive to cefpodoxime proxetil, particularly:
- Acute otitis media.
- Tonsillitis and Pharyngitis.
- Sinusitis.
- Lower respiratory tract infections.
- Uncomplicated skin and skin structure infections. Abscesses should be surgically drained as clinically indicated.
- Uncomplicated urinary tract infections.
Contraindications
- Known allergy to cephalosporins antibiotics.
- Children with phenylketonuria, since the formulation contains aspartame.
Warning
- The doctor should be immediately notified of the appearance of any allergic manifestation during the treatment (cutaneous eruption, pruritis.
- There is a possibility of allergy (in 5 to 10% of cases) in subjects sensitive to penicillins. Notify your doctor of any allergic symptom or allergy, which has already occurred during a previous treatment with penicillin.
Precaution of use
- Renal impairment (see dosage).
- Orelox suspension is not recommended for children below 15 days of age.
Side effects
As with all active substances, the drug may in some children cause effects of varying degrees of intensity; more particularly diarrhoea, but also abdominal pain, nausea, vomiting and cutaneous eruptions.
Dosage and administration
It is recommended to administer the product during a meal.
The average recommended dosage is 8 mg per kg per day to be taken in two divided doses at 12 hours intervals. Beyond 200 mg per day (25 kg), the 100 mg tablet may be used.
For administration, please use the calibrated spoon where the dosage cone has the calibration marks in kg (from 5 to 25) corresponding to the child weight. For example the calibration mark “12” corresponds to the quantity to be administered to a 12 kg child twice a day.
