Loprin (Aspirin) in Pregnancy and Lactation

Pregnancy

Although clinical and epidemiological evidence suggests the safety of Loprin (aspirin) for use in pregnancy, caution should be exercised when considering use in pregnant patients. Maternal use of aspirin prior to birth may increase the risk of intracranial haemorrhage in premature or low birth weight infants and may contribute to maternal and neonatal bleeding. Regular use of high does could impair platelet function and produce hypoprothrombinaemia in the infant if neonatal Vitamin K stores are low. Prolonged pregnancy & labour, with increased bleeding before & after delivery, decreased birth weight and increased rate of stillbirth have been reported with high blood salicylate levels. With high doses there may be premature closure of the ductus arteriosus and possible persistent pulmonary hypertension in the newborn. Analgesic doses of aspirin should be avoided during the last trimester of pregnancy.

Lactation

As Loprin (aspirin) is excreted in breast milk, aspirin should not be taken by patients who are breast-feeding, as there is a risk of Reye's syndrome in the infant. High maternal doses may impair platelet function in the infant.

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Free Prescription Drugs Information by Dr.Thomas Williams