When to Avoid Btrol (Tranexamic Acid)?
- In patients with acquired defective colour vision, since this prohibits measuring one end point that should be followed as a measure of toxicity (see warning)
- In patients with subarachnoid hemorrhage. Anecdotal experience indicates that cerebral edema and cerebral infarction may be caused by Btrol in such patients.
- In patients with active intravascular clotting.
- Massive haematuria from upper renal tract as may cause ureteric thrombotic obstruction.
Warnings
For patients who are to be treated continually for longer than several days, an ophthalmological examination, including visual acuity, colour vision, eye-ground and visual fields, is advised, before commencing and at regular intervals during the course of treatment. Btrol should be discontinued if changes in examination results are found. No retinal changes have been reported in eye examinations in patients treated with tranexamic acid for weeks to months in clinical trials. Rare, but if any of the following signs and symptoms of blood clot occur consult your doctor as soon as possible; Headache (severe and sudden), sudden loss of coordination, pains in chest, groin, or legs, especially the calves, sudden shortness of breath, slurred speech (sudden), vision changes (sudden), weakness or numbness in arm or leg.
